Bolivia is currently 8th on the table with 8 points. Despite the fact they are second from the bottom, only 4 points separates them from fifth placed Venezuela (play-off place) and 5 points from fourth placed Uruguay (direct participation). I believe this is the crucial match for the Bolivians. A victory here will increase their chances to reach World Cup 2014 in Brazil. The home advantage is very important as the stadium Hernando Siles is one of the highest football arenas in the World, 3637 meters above sea level.
Argentina is on the top of the table and they are very close to secure place at World Cup 2012. The coach Alejandro Sabella is satisfied with the team performances. Many coaches before him had a problem to motivate the best World player Lionel Messi, but Sabella is on good way. I believe this is a special match for Messi from one particular reason. Bolivia is the only Conmebol side that have not conceded a goal from him.
I think Argentina will win. The home advantage is important in this encounter, but not crucial. The actual form is on Argentina side. Bolivia suffered a heavy 5:0 defeat from Colombia on Friday, while Argentina won 3:0 against Venezuela. Gonzalo Higuain was double scorer, while Messi scored the penalty shot.
Argentina is in excellent form at the moment, winning the last three qualifiers.
It is also important to be mentioned that Bolivia goalkeeper Carlos Arias will miss the game due to injury. His replacement will be Sergio Galarza, but his confidence is in question after conceded four goals on Friday. On contrary, Argentinian coach Sabella has Angel Di Maria available after completed a one-game suspension.
Considering the previously mentioned reasons, I believe Argentina will win.